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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D3
All Species:
5.76
Human Site:
S370
Identified Species:
18.1
UniProt:
Q8IZP1
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZP1
NP_001001417.5
549
62168
S370
P
E
Q
G
S
S
A
S
R
P
V
P
A
S
R
Chimpanzee
Pan troglodytes
XP_001173074
549
62288
S370
P
E
Q
G
S
S
A
S
R
P
V
P
A
S
R
Rhesus Macaque
Macaca mulatta
XP_001112605
584
64806
W409
E
D
Q
L
A
T
C
W
Q
A
E
H
P
A
E
Dog
Lupus familis
XP_544260
839
96074
H425
R
E
S
G
S
S
P
H
K
K
H
E
P
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80XC3
819
93555
A378
G
Q
L
P
P
E
S
A
C
V
N
H
L
S
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508840
842
96631
S395
G
Q
S
S
M
S
V
S
S
S
H
V
V
K
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GLZ0
342
39660
D175
Y
L
I
L
V
T
K
D
E
E
K
A
F
W
L
Zebra Danio
Brachydanio rerio
Q6PBU5
356
41604
E190
L
I
L
V
S
K
D
E
E
T
S
F
W
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
56.1
23.8
N.A.
24.9
N.A.
N.A.
25
N.A.
20.7
20.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98
63.1
37.6
N.A.
37.9
N.A.
N.A.
38.7
N.A.
35.1
33.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
33.3
N.A.
6.6
N.A.
N.A.
20
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
40
N.A.
26.6
N.A.
N.A.
26.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
25
13
0
13
0
13
25
13
0
% A
% Cys:
0
0
0
0
0
0
13
0
13
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
0
13
13
0
0
0
0
0
0
0
% D
% Glu:
13
38
0
0
0
13
0
13
25
13
13
13
0
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
13
13
0
0
% F
% Gly:
25
0
0
38
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
13
0
0
25
25
0
0
0
% H
% Ile:
0
13
13
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
13
13
0
13
13
13
0
0
13
0
% K
% Leu:
13
13
25
25
0
0
0
0
0
0
0
0
13
13
13
% L
% Met:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
13
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
13
% N
% Pro:
25
0
0
13
13
0
13
0
0
25
0
25
25
0
13
% P
% Gln:
0
25
38
0
0
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
13
0
0
0
0
0
0
0
25
0
0
0
0
0
38
% R
% Ser:
0
0
25
13
50
50
13
38
13
13
13
0
0
50
0
% S
% Thr:
0
0
0
0
0
25
0
0
0
13
0
0
0
0
0
% T
% Val:
0
0
0
13
13
0
13
0
0
13
25
13
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
13
0
0
0
0
13
13
0
% W
% Tyr:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _